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Third Generation EGFR Inhibitors

Third Generation EGFR Inhibitors: Overcoming EGFR Resistance and Toxicity Problems reviews current issues relating to the design;

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Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC

implemented Discusses critical resistant mechanisms seen in the clinic to 1st, 2nd and 3rd generation EGFR inhibitors Encompasses;

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Proteinkinase Inhibitors

covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book. Given its;

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Iressa-A Boon to Colon Cancer

The epidermal growth factor receptor (EGFR) is under investigation as a therapeutic target for cancers. Colon cancer cell lines are;

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Fighting Lung Cancer Through the HER Family of Surface Receptors

growth factor receptor (EGFR) is over-expressed in over 80% of non-small cell lung cancer. The presence of sensitising conformational mutations;

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Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL;

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Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies

Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies presents a description of the sensitizers used to overcome resistance to anti;

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Infections Related to Biologics An Issue of Infectious Disease Clinics of North America

malignancies; EGFR inhibitors and other Tyrosine kinase inhibitors for solid tumors; Targeting JAK-STAT signaling and complement pathway for;

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The Treatment of Myeloid Malignancies with Kinase Inhibitors, An Issue of Hematology/Oncology Clinics of North America

of chronic myelogenous leukemia; Mechanisms of resistance to ABL kinase inhibition in CML and the development of next generation ABL kinase;

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New Skin Toxicities for New Anticancer Therapies

profile. The inhibition of epidermal growth factor receptor (EGFR), vascular growth factor (VEGF) and BRAF represents major achievements;

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Cardio-oncology Related to Heart Failure, An Issue of Heart Failure Clinics

potential cause of Heart Failure; EGFR target based therapy; Amyloidosis; How to manage Heart Failure in a patient with cancer; Advanced HF/Txp;

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Phosphodiesterase Inhibitors

decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a;

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The role of EGFR in c-fos-dependent osteosarcoma formation

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Targeted Therapies in Lung Cancer

target these drivers. To date, several tyrosine kinase inhibitors have been approved to target the epidermal growth factor receptor (EGFR;

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mTOR Inhibition for Cancer Therapy: Past, Present and Future

clinical trials (including pivotal registration trials) already underway. Second-generation small-molecule inhibitors of the pathway have also;

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Corrosion Inhibitors in the Oil and Gas Industry

Provides comprehensive coverage of corrosion inhibitors in the oil and gas industries Conside;...

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Theory and Applications of Green Corrosion Inhibitors

The book presents theoretical insights, characterization tools and mechanisms of green corrosion inh;...

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Multicast in ThirdGeneration Mobile Networks

A hands-on tutorial on multicast in third-generation networks! In this book, the authors describe how to perform multicast, the one-to-many;

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Third Generation/Another Place/Go .. Generation/Another Place/Go. Hiroshima, CD

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Inhibitors in Patients with Haemophilia

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of;...

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CDMA Techniques for Third Generation Mobile Systems

CDMA Techniques for Third Generation Mobile Systems presents advanced techniques for analyzing and developing third generation mobile;

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Small Molecules in Oncology

of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book is the third edition of Small Molecules;

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Small Molecules in Oncology

cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book is the third edition of Small Molecules;

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Enzymes and Their Inhibitors: Drug Development

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors:;...

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Leukemias

Edited by experts from one of the world's largest leukemia centers, this book provides information o;...

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Environmentally Sustainable Corrosion Inhibitors

Environmentally Sustainable Corrosion Inhibitors: Fundamentals and Industrial Applications cover;...

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Targeted Therapies in Cancer

Besides surgery, radiation therapy, endocrine therapy or chemotherapy, which were widely used in can;...

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