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Pharmacokinetic Challenges in Drug Discovery

drug discovery process. One of the biggest challenges is the pharmacokinetic (PK) optimisation of drug candidates tailored and predicted to;

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Enzyme Inhibition in Drug Discovery and Development

This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both;

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Transporters in Drug Discovery and Development

Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide;

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Lead Optimization for Medicinal Chemists

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a;

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Basic Pharmacokinetics

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It;

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Physiologically Based Pharmacokinetic (PBPK) Model ing and Simulations

for improving drug discovery and development. This fully updated new edition covers key developments in the field of PBPK modelling and;

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Oral Bioavailability Assessment

bioavailability one of the most significant hurdles in drug discovery and development. Describes approaches to assess pharmacokinetics and how drug efflux;

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New Horizons in Predictive Drug Metabolism and Pharmacokinetics

important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and pharmacokinetics. Readers;

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Principles of CNS Drug Development

This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery;

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Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has;

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Pharmacokinetics in Drug Discovery and Development

areas. Fulfilling the need for a wide-ranging guide to the many existing subspecialties in this field, Pharmacokinetics in Drug Discovery and;

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Retrometabolic Drug Design and Targeting

challenges of today's drug discovery. Next, it discusses: * Basic concepts of the mechanisms of drug action * Drug discovery and development;

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In Silico Drug Discovery and Design

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview;

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In Silico Drug Discovery and Design

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview;

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Clinical Pharmacokinetics

. Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles;

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Biomarkers in Clinical Drug Development

Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference;

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Practical Medicinal Chemistry with Macrocycles

synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug;

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Pharmacokinetic Profiling in Drug Research

screened for 'drugability', i.e., for 'drug-like' properties such as good pharmacokinetic (PK) behavior. Pharmacokinetic profiling of bioactive;

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Innovations and Implementations of Computer Aided Drug Discovery Strategies in R

, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development;

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Handbook of Pharmacokinetic/Pharmacodynamic Correlation

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and;

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Handbook of Pharmacokinetic/Pharmacodynamic Correlation

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and;

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Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition

performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field's leading text for more than three;

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Artificial Intelligence in Drug Discovery

, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as;

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Clinical Pharmacokinetics

This is the fourth edition of Clinical Pharmacokinetics . The book is written for clinicians with experience in basic pharmacokinetic;

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The Science and Business of Drug Discovery

Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology;

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The Science and Business of Drug Discovery

Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology;

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The Science and Business of Drug Discovery

Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology;

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