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fate decisions such as leukaemic stem cell self-renewal and differentiation. This book reviews the genetic and epigenetic abnormalities that;
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cancer stem cells; genetic and epigenetic alterations that drive leukaemic stem cell self-renewal and others.;
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govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that;
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Growing evidence suggests that epigenetic mechanisms play a central role in stem cell biology and are vital for determining gene expression;
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technologies provide new discoveries. Topics covered are genetic and epigenetic regulation of stem cells, stem cell plasticity, stem cell regulation;
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in therapeutic applications. Stem cells are also the driving force of cancer where geneticepigenetic alterations culminate in tumorigenesis either;
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applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell;
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applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell;
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genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9;
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of genome stability. These include genetic and epigenetic responses to various stresses in exposed cells and organisms, bystander and, bystander;
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in the body, or only in certain cells? Is cancer a genetic or a stem-cell disease? We illustrate that cancer is a multicellular rather than a;
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progression results from accumulated genetic mutations and inheritable epigenetic modifications that enable clonal evolution and selection of new;
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Scientists believe that stem cells have the potential to revolutionize the treatment of numerous diseases and conditions. This guide covers;
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There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells;
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azacitidine (an epigenetic regulator) have undergone progressive development. Meanwhile, the novel concept of therapy targeting leukemic stem cells;
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applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal;
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. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that;
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of stemcell self-renewal and differentiation, the stem cell niche, and signaling and gene regulation in stem cells. Studies of embryonic;
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that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development;
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of stemcell self-renewal and differentiation, the stem cell niche, and signaling and gene regulation in stem cells. Studies of embryonic;
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stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to;
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that target them. The contributors review the normal functions of hematopoietic stem cells--the precursors to white blood cells--and then;
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links genetic factors with the environmental experiences that influence the traits and characteristics of an individual. What we eat, where we;
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international board of authors. Its chapters provide a comprehensive set of reviews covering such topics as the regulation of blood stem cell;
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This second edition provides techniques used to study of the underlying transcriptional programs of stem cells that promote self-renewal;
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described several technologies that are currently available to detect epigenetic changes. These technologies have lead to a better understanding;
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