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Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies;
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Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular;
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intracellular concentration of the drug due to an increased efflux or a decreased influx, and enzymatic modification or destruction of the drug. With;
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delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; the role of microRNAs;
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DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference;
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nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and;
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to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs.;
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resistance to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs. This book presents new and;
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antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations. A major obstacle to controlling cancer;
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Molecular Cancer Therapeutics covers state-of-the-art strategies to identify and develop cancer drug target molecules and lead inhibitors;
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of cancer drug resistance have yielded important information about how to circumvent this resistance to improve cancer chemotherapy and its;
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diverse disciplines in cancer biology, epidemiology, molecular biology, genetics, immunology, gerontology, and drug resistance to discuss the;
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chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings;
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of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy;
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Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an;
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of molecular markers in the diagnosis of breast cancer; breast cancer knowledge and risk factors; immuno-conjugates; multi-drug resistance as a problem;
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treatment for cancer had been cytotoxic chemotherapy, with drugs targeting rapidly dividing cells, including cancer cells but also certain normal;
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new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new;
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. Currently, there are no drugs available to treat or prevent metastatic cancer other than non-selective, toxic chemotherapy. With contributions from;
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This book is an introduction to cancer treatment, the basics of radio- and chemotherapy, drug actions, the eradication of cancer cells, and;
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This book is an introduction to cancer treatment, the basics of radio- and chemotherapy, drug actions, the eradication of cancer cells, and;
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, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new;
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and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier;
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, Quantitation of O6 -- Methylguanine, Therapeutic Responses to Chemotherapy, Profiles in Cancer, Neurodegenerative Diseases and Multiple Sclerosis.;
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transporters, helping pharmaceutical researchers discover drugs to counteract multidrug resistance in diseases like cancer.;
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