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. Readers receive a thorough overview of the major co-translational modifications (CTMs) and post-translational modifications (PTMs) of therapeutic;
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considerable downstream and isolation processes. Provides thorough insights into the post translational modifications (PTMs) of proteins;
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Post-translational Modifications That Modulate Enzyme Activity, Volume 626 in the Methods in Enzymology series, continues the legacy;
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These lysine-based modifications (e.g. acetylation, methylation, ubiquitination and SUMOylation) help to regulate a vast number of cellular;
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With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and;
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Addressing the folding of proteins to natural states as well as cotranslational and post translational modifications that effect function;
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monitor post-translational modifications and to measure the abundance of proteins within the cell with extreme sensitivity. While protein;
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in the field * A valuable reference source for all laboratories undertaking proteomics, mass spectrometry and post-translational modification;
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ability to express any protein, with relevant post-translational modifications, and be as easy to work with as E. coli. In Heterologous Gene;
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ability to express any protein, with relevant post-translational modifications, and be as easy to work with as E. coli. In Heterologous Gene;
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immunoprecipitation (ChIP) assay Transcriptional elongationRegulation by post-translational modificationsRegulatory networks and;
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Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic;
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, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and;
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Protein Expression: A Practical Approach and its companion volume Post-translational Modification: A Practical Approach complete the mini;
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The formation of disulphide bonds is probably the most influential modification of proteins. These bonds are unique among post;
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therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other;
Vergelijkbare producten zoals Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases
in the management of human disease, this book is timely and relevant for basic and translational researchers, as well as clinicians alike.;
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characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters;
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The third volume of the Chromosomal Nonhistone Proteins treatise deals with the isolation and analysis of chromosomal proteins in general;
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or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins;
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, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers;
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, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and;
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in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr;
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in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr;
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molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some;
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of therapeutic proteins. To that end, plants have emerged in the past decade as a suitable alternative to the current production systems, and today their;
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