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Chromatin Proteins and Transcription Factors as Therapeutic Targets

Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and;

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Eukaryotic Transcription Factors

transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between;

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Chromatin Dynamics in Cellular Function

modifications (methylation, ubiquitylation) and their functional consequences, transcription and histone dynamics, roles of chromatin remodeling factors;

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Proteins in Eukaryotic Transcription

Protein Transcription is a key element of cellular and organ regulation. Proteins in Eukaryotic Transcription covers structure and function;

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Forkhead Transcription Factors

Forkhead Transcription Factors: Vital Elements in Biology and Medicine provides a unique platform for the presentation of novel work and;

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New Transcription Factors and Their Role in Diabetes and Therapy

therapeutic targets and their application to disease.*Applies molecular biology to transcriptional regulation of metabolism and obesity

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Chromatin Deregulation in Cancer

tumors, and prospects for the therapeutic modulation of chromatin. The contributors describe how histone proteins, histone-modifying enzymes;

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Chromatin Signaling and Diseases

changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin;

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Chromatin and Chromatin Remodeling Enzymes, Part B

DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodelling enzymes play an;

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Chromatin and Chromatin Remodeling Enzymes Part C

important role in gene transcription. Genetic assays of chromatin modification and remodeling Histone modifying enzymes

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Histone Deacetylase Inhibitors (HDIs)

condensed form of chromatin and preventing gene transcription. This book focuses on the use of HDIs for the treatment of lymphoid malignancies;

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Ion Channels as Therapeutic Targets, Part B

cutting-edge developments in protein chemistry and structural biology Discusses the use of ion channels as therapeutic targets

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Ion Channels as Therapeutic Targets, Part A

Ion Channels as Therapeutic Targets is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an;

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Therapeutic Proteins and Peptides

Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic;

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Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation

; (ii) Identifying Kglu as a new histone PTM and assessing the direct impact of histone Kglu on chromatin structure and dynamics; and (iii;

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Chromatin and Gene Regulation

of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by;

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Small-molecule Transcription Factor Inhibitors in Oncology

is gradually declining, transcription factor inhibition is the next hot topic for oncology research and merits much attention. This book highlights;

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New Developments in Chromatin Research

of chromatin as an integrative indicator of cell stress; analysing DNA damage and its repair throughout entire genomes; the cloning process, structural;

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Protein Engineering

PROTEIN ENGINEERING discusses topics, such as introduction to proteins like proteases, insulin, transcription factors etc. and continues;

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MADS box genes in Arabidopsis

are sequence-specific DNA-binding proteins that are capable of activating and/or repressing transcription. Therefore, studying transcription;

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Transcriptional Regulation

detailed volume explores promoter elements, transcription factors, and preinitiation complex (PIC) assembly, chromatin structure, chromatin;

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Drug Discovery in Cancer Epigenetics

cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which;

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Nucleosomes, Histones and Chromatin Part A

in the field. The first of 2 volumes covering nucleosomes, histones and chromatin, it has chapters on methods applied to the study of protein;

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Transcription Factors

, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization;

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Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for;

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Pharmaceutical Formulation Development of Peptides and Proteins

The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a;

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Phosphodiesterases as Drug Targets

and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts;

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